Palmitoyl Tripeptide-1 — INCI Palmitoyl Tripeptide-1, also called Pal-GHK, CAS 147732-56-7 — is a lipidated "matrikine" signal peptide. It pairs the GHK tripeptide with a palmitic acid chain that improves skin affinity, and is used in anti-aging and firming products to support a smoother, firmer appearance.
Key specifications
- CAS No.: 147732-56-7
- INCI: Palmitoyl Tripeptide-1
- Appearance: white to off-white powder
- Purity: cosmetic grade, typically reported by HPLC
- Solubility: the palmitoyl chain makes it lipophilic; often pre-dispersed or used in the emulsion phase
Typical use levels
Signal peptides like Pal-GHK work at low levels — commonly a fraction of a percent of the active. It is frequently blended with Palmitoyl Tetrapeptide-7 (the well-known "Matrixyl 3000" style pairing). Add during the cool-down phase and keep processing temperatures moderate.
Formulation notes
- Solubilise the palmitoyl peptide appropriately (it is not freely water-soluble).
- Add late, keep pH mild, and run a full stability and preservative-efficacy test.
- Store the raw material sealed, cool, dry and away from light.
Sourcing checklist
- Batch-specific COA with HPLC assay and stated method;
- MSDS/SDS and, for high-value lots, an HPLC chromatogram;
- MOQ, packaging (1 kg / 5 kg / 25 kg) and lead time;
- An evaluation sample for bench testing.
WYOO manufactures and exports Palmitoyl Tripeptide-1, cosmetic grade, with COA and MSDS on every batch and MOQ from 1 kg. Request a sample and current pricing.