Should I order GHK-Cu as the HCl or the acetate salt?

Both deliver Copper Tripeptide-1. The choice depends on your formulation base, regional preference and documentation. Tell the supplier the application and let them recommend the salt; the COA should state the salt form and the HPLC method.

What is the MOQ and lead time for cosmetic-grade GHK-Cu?

WYOO supplies GHK-Cu from 50 g with tiered pricing at 100 g, 500 g and 1 kg. In-stock lots ship in 5 to 10 working days after payment, by T/T with 30% deposit and 70% before shipment. Qualified companies can request a free 5 g sample.

Why does my GHK-Cu formula lose its blue colour?

Colour loss usually means the copper complex has been disrupted, most often by strong chelators, reducing agents such as high-dose ascorbic acid, or a pH outside the mildly acidic-to-neutral window. Check compatibility of the base and run a stability test before scaling up.

Copper Tripeptide-1 (GHK-Cu): Formulation Guide, Stability & Bulk Sourcing

Copper Tripeptide-1 — INCI Copper Tripeptide-1, widely known as GHK-Cu, CAS 89030-95-5 — is the copper complex of the tripeptide glycyl-L-histidyl-L-lysine (GHK). It is prized in skincare for its role in skin-repair, firming and renewal formulations, and is instantly recognisable by its blue colour.

Key specifications

CAS No.: 89030-95-5
INCI: Copper Tripeptide-1
Appearance: blue crystalline powder
Salt forms: commonly supplied as the hydrochloride (HCl) or acetate salt
Solubility: water-soluble

Typical use levels

GHK-Cu is typically used at 0.05–2% in the water phase. Because copper drives both the colour and the activity, a small amount goes a long way; higher levels deepen the blue tint of the finished product, which formulators either feature or offset.

Stability — the pitfalls to plan for

Copper peptides are more formulation-sensitive than many actives, so plan the base around them:

pH: keep to a mildly acidic-to-neutral window; extreme pH destabilises the complex.
Strong chelators & reducing agents: ingredients such as high-dose ascorbic acid (vitamin C) can strip or reduce the copper, breaking the complex. Separate them or use derivatives.
Sulfur compounds and strong anionics: can interact with copper — test compatibility.
Colour: the blue tint is normal; keep it in mind for pack and marketing.
Storage of raw material: sealed, cool, dry and away from light.

HCl vs acetate — which to order

Both salt forms deliver GHK-Cu; the choice usually comes down to your formulation base, regional preference and documentation. When in doubt, tell your supplier the application and let them recommend the salt and grade.

Sourcing checklist

Confirm salt form (HCl or acetate) and purity (with HPLC method on the COA);
Ask for a batch COA, MSDS and an HPLC chromatogram;
Confirm MOQ, packaging and lead time;
Request a sample to verify colour, solubility and purity.

WYOO is a sourcing partner with audited partner factories, not a manufacturer. We supply cosmetic-grade Copper Tripeptide-1 in both HCl and acetate salts, with a COA and MSDS on every batch, MOQ from 50 g, lead time 5 to 10 working days after payment for in-stock lots, payment by T/T (30% deposit, 70% before shipment) and free 5 g samples for qualified companies. Quotes are provided in English, Chinese, Spanish, German or French. Contact us for a sample and current pricing.

Frequently asked questions

Should I order GHK-Cu as the HCl or the acetate salt?: Both deliver Copper Tripeptide-1. The choice depends on your formulation base, regional preference and documentation. Tell the supplier the application and let them recommend the salt; the COA should state the salt form and the HPLC method.
What is the MOQ and lead time for cosmetic-grade GHK-Cu?: WYOO supplies GHK-Cu from 50 g with tiered pricing at 100 g, 500 g and 1 kg. In-stock lots ship in 5 to 10 working days after payment, by T/T with 30% deposit and 70% before shipment. Qualified companies can request a free 5 g sample.
Why does my GHK-Cu formula lose its blue colour?: Colour loss usually means the copper complex has been disrupted, most often by strong chelators, reducing agents such as high-dose ascorbic acid, or a pH outside the mildly acidic-to-neutral window. Check compatibility of the base and run a stability test before scaling up.